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- Title
Primary angiosarcoma arising in an angiomyolipoma of the kidney: case report and literature review.
- Authors
Guan, Hongwei; Zhang, Lizhi; Zhang, Qiuping; Qi, Wenjing; Xie, Suling; Hou, Jinping; Wang, Huali
- Abstract
Background: Primary angiosarcoma of the kidney is a rare and aggressive malignant tumor presenting with a recognizable vascular differentiation. Its prognosis is fatal and the pathogenesis remains unclear. Renal angiomyolipoma is a relatively infrequent renal cortical neoplasm and is composed of variable proportions of adipose tissue, spindle cells, epithelioid smooth muscle cells and abnormal thick-walled blood vessels. Case presentation: Here, we reported a case in which a 64-year-old woman presenting with the chief complaint of a progressively enlarged mass in the left abdomen. Abdominal computed tomography confirmed presence of a tumor measuring 18 cm × 11 cm in the left posterior renal fascia. Microscopic examination and immunohistochemical staining confirmed co-existence of angiomyolipoma and angiosarcoma. Furthermore, the two components interspersed with each other and there were transitional zones between them. Conclusions: In this case, we described for the first time a primary renal angiosarcoma possibly arising in a pre-existing angiomyolipoma of the kidney.
- Subjects
ANGIOMYOLIPOMA; COMPUTED tomography; IMMUNOSTAINING; ADIPOSE tissues
- Publication
Diagnostic Pathology, 2018, Vol 13, Issue 1, pN.PAG
- ISSN
1746-1596
- Publication type
Case Study
- DOI
10.1186/s13000-018-0730-z