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- Title
New Indices to Detect Acute Kidney Injury in Coronary Artery Disease Patients.
- Authors
Shaik, Abdul Samad; Lakshmi, V. S. Bharathi
- Abstract
Objectives: Pre-procedure liver impairment has been revealed as a poor prognostic factor post-percutaneous coronary intervention (PCI). Recent investigations discovered that the aspartate aminotransferase-to-alanine aminotransferase ratio (De-Ritis ratio) indicates the severity of liver impairment and was related to adverse outcomes. We aimed to evaluate the predictive value of the De-Ritis ratio for contrast-associated acute kidney injury (CA-AKI). Materials and Methods: We prospectively enrolled 150 patients undergoing elective PCI between June 2022 and August 2022. Contrast-induced AKI: It is defined as an acute decline in renal function, defined as an increase in creatinine of =0.5 mg/dL or =25% compared to baseline. It usually develops 24-72 h post administration of an IV contrast agent in the absence of other identifiable causes. Results: The incidence of CA-AKI was 8% (n = 12). The De-Ritis ratio >1.30 was identified as the best cutoff value for CA-AKI prediction. Conclusion: The De-Ritis ratio was an independent risk factor for CA-AKI in patients undergoing elective PCI.
- Subjects
INDIA; LIVER physiology; ANALYSIS of triglycerides; PREDICTIVE tests; RISK assessment; PEARSON correlation (Statistics); CREATININE; CIRRHOSIS of the liver; T-test (Statistics); ASPARTATE aminotransferase; HEMOGLOBINS; ACUTE kidney failure; HOSPITAL mortality; DESCRIPTIVE statistics; CHI-squared test; LONGITUDINAL method; LOW density lipoproteins; ALANINE aminotransferase; PERCUTANEOUS coronary intervention; CORONARY artery disease; COMPARATIVE studies; CONTRAST media; DISEASE complications
- Publication
Indian Journal of Cardiovascular Disease in Women - WINCARS, 2024, Vol 9, Issue 1, p10
- ISSN
2455-7854
- Publication type
Article
- DOI
10.25259/IJCDW_15_2023