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- Title
Comparison of retroperitoneal liposarcoma extending into the inguinal canal and inguinoscrotal liposarcoma.
- Authors
Rhu, Jinsoo; Cho, Chan Woo; Lee, Kyo Won; Park, Hyojun; Park, Jae Berm; Choi, Yoon-La; Kim, Sung Joo
- Abstract
<bold>Background: </bold>This study was designed to analyze differences between retroperitoneal liposarcoma (RLPS) extending into the inguinal canal and inguinoscrotal liposarcoma.<bold>Methods: </bold>We retrospectively reviewed the records for patients who were managed for inguinal liposarcoma at Samsung Medical Center, a tertiary hospital, between January 1998 and December 2016. Patient data on demographics, tumour location, surgery, adjuvant therapy, histology, recurrence and death were collected. We used Mann-Whitney, Fisher exact and Kaplan-Meier log-rank tests to analyze differences between groups.<bold>Results: </bold>Seven of 179 (3.9%) patients with abdominal liposarcoma had inguinoscrotal liposarcoma, and 6 of 168 (3.6%) patients with RLPS had extension to the inguinal canal. No differences were observed between groups in sex (p > 0.99), mean age (49.7 ± 6.4 yr v. 52.1 ± 12.5 yr, p = 0.37), laterality (p > 0.99) or scrotal involvement (40.0% v. 66.7%, p = 0.57). The RLPS group had significantly larger tumours than the inguinoscrotal group (27.9 ± 6.8 cm v. 7.8 ± 4.2 cm, p = 0.001). Postoperative complications were significantly more common in the RLPS group (n = 4, 83.3%); patients in the inguinoscrotal group experienced no postoperative complications (p = 0.021). Log-rank tests showed that the groups had no statistical differences in disease-free survival (p = 0.94) or overall survival (p = 0.10). However, inoperable disease-free survival was significantly poorer in the RLPS group (p = 0.010).<bold>Conclusion: </bold>Although initial signs and symptoms can be similar, RLPS extending into the inguinal canal was associated with significantly higher morbidity and mortality than inguinoscrotal liposarcoma.
- Subjects
ABDOMEN; CANCER invasiveness; COMPARATIVE studies; LIPOSARCOMA; RESEARCH methodology; MEDICAL cooperation; RESEARCH; SCROTUM; RETROPERITONEUM; EVALUATION research; RETROSPECTIVE studies; MALE reproductive organs; TUMORS
- Publication
Canadian Journal of Surgery, 2017, Vol 60, Issue 5, p5917
- ISSN
0008-428X
- Publication type
journal article
- DOI
10.1503/cjs.005917