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- Title
Response to Comment on Adam et al. Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues. Diabetes 2016;65:3776-3785.
- Authors
Adam, Jonathan; Brandmaier, Stefan; Troll, Martina; Rotter, Markus; Mohney, Robert P.; Heier, Margit; Adamski, Jerzy; Yixue Li; Neschen, Susanne; Kastenmüller, Gabi; Suhre, Karsten; Ankerst, Donna; Meitinger, Thomas; Rui Wang-Sattler; Li, Yixue; Wang-Sattler, Rui
- Abstract
The article offers information on beneficial effects of citrulline in diseases such as nonalcoholic fatty liver disease and the interaction of citrulline and metformin. Topics discussed include association between insulin resistance and high citrulline, underlying mechanisms that would benefit from several investigations including gut tissues and kidney, and type 2 diabetes.
- Subjects
FATTY liver; CITRULLINE; METFORMIN; INSULIN resistance; KIDNEYS; TYPE 2 diabetes; ANIMAL experimentation; COMPARATIVE studies; HYPOGLYCEMIC agents; RESEARCH methodology; MEDICAL cooperation; MICE; RESEARCH; EVALUATION research
- Publication
Diabetes, 2017, Vol 66, Issue 5, pe3
- ISSN
0012-1797
- Publication type
letter
- DOI
10.2337/dbi17-0010