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Gold compounds as cysteine protease inhibitors: perspectives for pharmaceutical application as antiparasitic agents.
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- BioMetals, 2017, v. 30, n. 2, p. 313, doi. 10.1007/s10534-017-0007-0
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- Article
Synthesis and Cytotoxicity of Diarylpentanoids against Sensitive CCRF‐CEM and Multidrug‐Resistant CEM/ADR5000 Leukemia Cells.
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- Chemistry & Biodiversity, 2022, v. 19, n. 2, p. 1, doi. 10.1002/cbdv.202100451
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- Article
Discovery of benzimidazole‐based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis.
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- Chemical Biology & Drug Design, 2018, v. 92, n. 3, p. 1585, doi. 10.1111/cbdd.13326
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- Article
Ensemble‐based ADME–Tox profiling and virtual screening for the discovery of new inhibitors of the <italic>Leishmania mexicana</italic> cysteine protease CPB2.8ΔCTE.
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- Chemical Biology & Drug Design, 2018, v. 91, n. 2, p. 597, doi. 10.1111/cbdd.13124
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- Article
Dipeptide Nitrile CD34 with Curcumin: A New Improved Combination Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 8477, doi. 10.3390/ijms24108477
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- Article
Investigation of the Compatibility between Warheads and Peptidomimetic Sequences of Protease Inhibitors—A Comprehensive Reactivity and Selectivity Study.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 7226, doi. 10.3390/ijms24087226
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- Article
Chemical Space Virtual Screening against Hard-to-Drug RNA Methyltransferases DNMT2 and NSUN6.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 7, p. 6109, doi. 10.3390/ijms24076109
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- Article
Drug Combination Studies of the Dipeptide Nitrile CD24 with Curcumin: A New Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14470, doi. 10.3390/ijms232214470
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- Article
Novel Class of Proteasome Inhibitors: In Silico and In Vitro Evaluation of Diverse Chloro(trifluoromethyl)aziridines.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12363, doi. 10.3390/ijms232012363
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- Article
Comparison of the separation of aziridine isomers applying heptakis(2,3-di-O-methyl-6-sulfato)β-CD and heptakis(2,3-di-O-acetyl-6-sulfato)β-CD in aqueous and nonaqueous systems.
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- Electrophoresis, 2005, v. 26, n. 20, p. 3897, doi. 10.1002/elps.200500176
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- Article
Anti-trypanosomal activities and structural chemical properties of selected compound classes.
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- Parasitology Research, 2015, v. 114, n. 2, p. 501, doi. 10.1007/s00436-014-4210-4
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- Article
Subnanomolar Cathepsin S Inhibitors with High Selectivity: Optimizing Covalent Reversible α‐Fluorovinylsulfones and α‐Sulfonates as Potential Immunomodulators in Cancer.
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- ChemMedChem, 2023, v. 18, n. 15, p. 1, doi. 10.1002/cmdc.202300160
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- Article
Structure-Activity Relationships of Benzamides and Isoindolines Designed as SARS-CoV Protease Inhibitors Effective against SARS-CoV-2.
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- ChemMedChem, 2021, v. 16, n. 2, p. 340, doi. 10.1002/cmdc.202000548
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Front Cover: Structure‐Activity Relationships of Benzamides and Isoindolines Designed as SARS‐CoV Protease Inhibitors Effective against SARS‐CoV‐2 (2/2021)
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- ChemMedChem, 2021, v. 16, n. 2, p. 301, doi. 10.1002/cmdc.202000987
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- Article
Peptidyl Vinyl Ketone Irreversible Inhibitors of Rhodesain: Modifications of the P2 Fragment.
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- ChemMedChem, 2020, v. 15, n. 16, p. 1552, doi. 10.1002/cmdc.202000360
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- Article
Development of Novel Benzodiazepine‐Based Peptidomimetics as Inhibitors of Rhodesain from Trypanosoma brucei rhodesiense.
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- ChemMedChem, 2020, v. 15, n. 11, p. 995, doi. 10.1002/cmdc.202000158
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- Article
Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase A.
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- ChemMedChem, 2020, v. 15, n. 10, p. 839, doi. 10.1002/cmdc.201900687
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- Article
Protocol for Rational Design of Covalently Interacting Inhibitors.
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- ChemPhysChem, 2014, v. 15, n. 15, p. 3226, doi. 10.1002/cphc.201402542
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- Article
Die Bedeutung ionischer Bindungsanteile in Schwefeldioxid - Bindungsordnungen aus Röntgenbeugungsdaten.
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- Angewandte Chemie, 2012, v. 124, n. 27, p. 6880, doi. 10.1002/ange.201200745
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- Article
Peptidyl nitroalkene inhibitors of main protease rationalized by computational and crystallographic investigations as antivirals against SARS-CoV-2.
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- Communications Chemistry, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42004-024-01104-7
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- Article
Identification of the protease inhibitor miraziridine A in the Red sea sponge Theonella swinhoei.
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- Pharmacognosy Research, 2012, v. 4, n. 1, p. 63, doi. 10.4103/0974-8490.91047
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- Article
β-Lactam Derivatives as Enzyme Inhibitors: 1-Peptidyl Derivatives of 4-Phenylazetidin-2-one as Inhibitors of Elastase and Papain.
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- Archiv der Pharmazie, 2000, v. 333, n. 8, p. 243, doi. 10.1002/1521-4184(20008)333:8<243::AID-ARDP243>3.0.CO;2-O
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- Article
Aziridine-2,3-dicarboxylic Acid Derivatives as Inhibitors of Papain.
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- Archiv der Pharmazie, 1996, v. 329, n. 5, p. 239, doi. 10.1002/ardp.19963290504
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- Article
BANΔIT: B'‐Factor Analysis for Drug Design and Structural Biology.
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- Molecular Informatics, 2021, v. 40, n. 1, p. 1, doi. 10.1002/minf.202000144
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- Article
Metal Ions as Co-Inhibitors of Serine Proteases: A New Approach in the Search for Specific High-Affinity Ligands.
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- Angewandte Chemie International Edition, 1998, v. 37, n. 13/14, p. 1830, doi. 10.1002/(SICI)1521-3773(19980803)37:13/14<1830::AID-ANIE1830>3.0.CO;2-F
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- Article
E/Z Diastereoselective Enzymatic Hydrolysis of Esters and Diesters.
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- Angewandte Chemie International Edition, 1993, v. 32, n. 4, p. 572, doi. 10.1002/anie.199305721
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- Article
Natural Product Repertoire of the Genus Amphimedon.
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- Marine Drugs, 2019, v. 17, n. 1, p. 19, doi. 10.3390/md17010019
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- Article
Cytotoxicity of Endoperoxides from the Caribbean Sponge Plakortis halichondrioides towards Sensitive and Multidrug-Resistant Leukemia Cells: Acids vs. Esters Activity Evaluation.
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- Marine Drugs, 2017, v. 15, n. 3, p. 63, doi. 10.3390/md15030063
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- Article
Identification of Plakortide E from the Caribbean Sponge Plakortis halichondroides as a Trypanocidal Protease Inhibitor using Bioactivity-Guided Fractionation.
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- Marine Drugs, 2014, v. 12, n. 9, p. 2614, doi. 10.3390/md12052614
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- Article
Identification of Plakortide E from the Caribbean Sponge Plakortis halichondroides as a Trypanocidal Protease Inhibitor using Bioactivity-Guided Fractionation.
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- Marine Drugs, 2014, v. 12, n. 5, p. 2614, doi. 10.3390/md12052614
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- Article
Antioxidant and Anti-Protease Activities of Diazepinomicin from the Sponge-Associated Micromonospora Strain RV115.
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- Marine Drugs, 2012, v. 10, n. 10, p. 2208, doi. 10.3390/md10102208
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- Article
New Tetromycin Derivatives with Anti-Trypanosomal and Protease Inhibitory Activities.
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- Marine Drugs, 2011, v. 9, n. 10, p. 1682, doi. 10.3390/md9101682
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- Article
Can Experimental Electron-Density Studies be Used as a Tool to Predict Biologically Relevant Properties of Low-Molecular Weight Enzyme Ligands?
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- Zeitschrift für Anorganische und Allgemeine Chemie, 2013, v. 639, n. 11, p. 1905, doi. 10.1002/zaac.201200518
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- Article
Inhibitory effects of 190 compounds against SARS‐CoV‐2 M<sup>pr</sup><sup>o</sup> protein: Molecular docking interactions.
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- Archiv der Pharmazie, 2023, v. 356, n. 8, p. 1, doi. 10.1002/ardp.202300207
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- Article
Selective noncovalent proteasome inhibiting activity of trifluoromethyl‐containing gem‐quaternary aziridines.
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- Archiv der Pharmazie, 2023, v. 356, n. 7, p. 1, doi. 10.1002/ardp.202300174
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- Article
Thiirancarboxamides as Inhibitors of Papain.
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- Archiv der Pharmazie, 2004, v. 337, n. 2, p. 90, doi. 10.1002/ardp.200300820
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- Article
Metabolomics analysis and biological investigation of three Malvaceae plants.
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- Phytochemical Analysis, 2020, v. 31, n. 2, p. 204, doi. 10.1002/pca.2883
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- Article
Substitution-Induced Mechanistic Switching in S N Ar-Warheads for Cysteine Proteases.
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- Molecules, 2024, v. 29, n. 11, p. 2660, doi. 10.3390/molecules29112660
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- Article
Computational Design, Synthesis, and Biophysical Evaluation of β-Amido Boronic Acids as SARS-CoV-2 M pro Inhibitors.
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- Molecules, 2023, v. 28, n. 5, p. 2356, doi. 10.3390/molecules28052356
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- Article
Discovery of a Novel Trifluoromethyl Diazirine Inhibitor of SARS-CoV-2 M pro.
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- Molecules, 2023, v. 28, n. 2, p. 514, doi. 10.3390/molecules28020514
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- Article
Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis.
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- Molecules, 2022, v. 27, n. 12, p. 3765, doi. 10.3390/molecules27123765
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- Article
Graphical Workflow System for Modification Calling by Machine Learning of Reverse Transcription Signatures.
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- Frontiers in Genetics, 2019, p. 1, doi. 10.3389/fgene.2019.00876
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- Article
Fly versus man: evolutionary impairment of nucleolar targeting affects the degradome of Drosophila's Taspase1.
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- FASEB Journal, 2015, v. 29, n. 5, p. 1973, doi. 10.1096/fj.14-262451
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- Article
Identification of novel small-molecular inhibitors of Staphylococcus aureus sortase A using hybrid virtual screening.
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- Journal of Antibiotics, 2022, v. 75, n. 6, p. 321, doi. 10.1038/s41429-022-00524-8
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- Article
Inhibition of cysteine proteases by peptides containing aziridine-2,3-dicarboxylic acid building blocks.
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- Biopolymers, 1999, v. 51, n. 1, p. 87, doi. 10.1002/(SICI)1097-0282(1999)51:1<87::AID-BIP10>3.0.CO;2-Z
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- Article
Novel Opportunities for Cathepsin S Inhibitors in Cancer Immunotherapy by Nanocarrier-Mediated Delivery.
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- Cells (2073-4409), 2020, v. 9, n. 9, p. 2021, doi. 10.3390/cells9092021
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- Article
Chemical biology and medicinal chemistry of RNA methyltransferases.
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- Nucleic Acids Research, 2022, v. 50, n. 8, p. 4216, doi. 10.1093/nar/gkac224
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- Article
Approaching an experimental electron density model of the biologically active trans-epoxysuccinyl amide group-Substituent effects vs. crystal packing.
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- Journal of Physical Organic Chemistry, 2017, v. 30, n. 11, p. n/a, doi. 10.1002/poc.3683
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- Article
Cathepsin B in Antigen-Presenting Cells Controls Mediators of the Th1 Immune Response during Leishmania major Infection.
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- PLoS Neglected Tropical Diseases, 2014, v. 8, n. 9, p. 1, doi. 10.1371/journal.pntd.0003194
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- Article
Cathepsin B in Antigen-Presenting Cells Controls Mediators of the Th1 Immune Response during Leishmania major Infection.
- Published in:
- PLoS Neglected Tropical Diseases, 2014, v. 8, n. 9, p. 1, doi. 10.1371/journal.pntd.0003194
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- Article