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- Title
Klebsiella Brain Abscess in Adults.
- Authors
Liliang, P.-C.; Lin, Y.-C.; Su, T.-M.; Rau, C.-S.; Lu, C.-H.; Chang, W.-N.; Lee, T.-C.; Chen, H.-J.
- Abstract
Background: We analyzed the clinical, manifestations and therapeutic outcomes of Kiebsiella brain abscesses. Patients and Methods: The clinical, data of 15 patients with Kiebsiella brain abscesses, retrospectively collected over a 14-year period, were studied. Results: The 15 patients included 13 cases of Kiebsiella pneumoniae infection and two cases of Kiebsiella oxytoca. All but one case were community-acquired infections. Locations of all of these abscesses were supratentorial, 12 cases involved a single abscess, and three involved multiple abscesses. Gas formation was also found in two cases (13%). Common predisposing factors included metastatic spread, chronic otitis media and neurosurgical. procedures. Among these 15 patients, 11 were treated surgically and four received antibiotics alone. In total, 11 patients survived and four died, with an overall mortality rate of 26.7%. Conclusion: The clinical, presentations and therapeutic outcomes varied according to the different Kiebsiella species. While debilitating diseases were common in K. pneumoniae infections, they were not common in K. oxytoca infection. And while metastatic septic abscess is a well-known, devastating complication of K. pneumoniae septicemia, usually seen as a brain abscess with a gas-forming appearance, all of these K. oxytoca infections had both otogenic infections and more favorable outcomes.
- Subjects
KLEBSIELLA; ENTEROBACTERIACEAE; ULCERS; ABSCESSES; INFECTION; OTITIS media
- Publication
Infection, 2001, Vol 29, Issue 2, p81
- ISSN
0300-8126
- Publication type
Article
- DOI
10.1007/s15010-001-0069-2