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- Title
No effect of a liquid diet in the management of patients with stricturing Crohn's disease.
- Authors
Marafini, Irene; Salvatori, Silvia; Troncone, Edoardo; Scarozza, Patrizio; Fantini, Elisa; Monteleone, Giovanni
- Abstract
Purpose: Patients with stricturing Crohn's disease (CD) may experience episodes of intestinal sub-occlusions, which in many cases lead to surgery. The aim of this study was to examine whether adding a liquid diet to medical therapy could improve the management of patients with stricturing CD. Methods: Medical records of CD outpatients with a small bowel stricture, either receiving (group 1) or not (group 2) a 24-h liquid diet every 10-14 days, were retrospectively analyzed. Number of sub-occlusive episodes, frequency, and timing of intestinal resections for strictures were analyzed. Results: During the 12-month follow-up, there was no significant difference in the occurrence of new sub-occlusive episodes between the 2 groups (10/37 patients (27%) in group 1 vs 9/45 patients (20%) in group 2). Similarly, the number of patients undergoing bowel resections for sub-occlusive episodes non-responsive to medical therapy did not statistically differ between the two groups (9 patients (24.3%) in group 1 vs 7 patients (15.5%) in group 2). In group 1, surgeries were equally distributed along the 12-months of follow-up, while 85.7% of patients in group 2 underwent intestinal resection within the first 3 months of follow-up. Conclusion: Adding a liquid diet to medical therapy does not help management of patients with stricturing CD.
- Subjects
CROHN'S disease; DIET therapy; INFLAMMATORY bowel diseases; ENTEROSCOPY
- Publication
International Journal of Colorectal Disease, 2020, Vol 35, Issue 10, p1881
- ISSN
0179-1958
- Publication type
Article
- DOI
10.1007/s00384-020-03650-7