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- Title
Immunopathology of Alkaline Phosphatase Isozymes in Seminoma.
- Authors
Yamamoto, Hajime; Uchibayashi, Tadao; Koshida, Kiyoshi; Hirano, Kazuyuki; Hisazumi, Haruo
- Abstract
An immunohistopathological study using monoclonal antibodies for alkaline phosphatases demonstrated placental alkaline phosphatase (PLAP)-like substance in the tumor cells of 11 pure seminomas, 1 seminoma with embryonal carcinoma and 1 seminoma metastasis. Liver alkaline phosphatase (LAP) could also be demonstrated in all seminomas but a third intestinal alkaline phosphatase (IAP) was not demonstrable in any tumor. The PLAP-like substance and LAP had considerable enzyme activities. This provides two tumor markers of seminomas detectable in histopathological specimens. Copyright © 1993 S. Karger AG, Basel
- Publication
Urologia Internationalis, 1993, Vol 50, Issue 1, p33
- ISSN
0042-1138
- Publication type
Article
- DOI
10.1159/000282444