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- Title
Bent Benzocoumarin Dyes that Fluoresce in Solution and in Solid State and Their Application to Bioimaging.
- Authors
Dai, Mingchong; Sarkar, Sourav; Song, Chang Wook; Reo, Ye Jin; Yang, Yun Jae; Ahn, Kyo Han
- Abstract
Organic fluorophores are essential in microscopic imaging of biological systems. New fluorophores with distinct features are in demand for bioimaging. Herein we report new bent benzocoumarin dyes that are fluorescent both in solution and in the solid state. The latter property enables us to form fluorescent nanoparticles with a mean size of 120–157 nm or larger depending on conditions. Some of the new dyes provide bright fluorescent images in cell, with formation of particulate spots that persist even after several washout procedures, and, furthermore, in tissue under two‐photon excitation at 900 nm. Such dyes have potential for the development of fluorescent probes for enhanced cellular fluorescence.
- Subjects
SOLID solutions; FLUORESCENT probes; IMAGING systems; NANOPARTICLE size; CELL imaging; FLUOROPHORES
- Publication
ChemPhotoChem, 2020, Vol 4, Issue 9, p721
- ISSN
2367-0932
- Publication type
Article
- DOI
10.1002/cptc.202000059