We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Correlation between Discharged Worms and Fecal Egg Counts in Human Clonorchiasis.
- Authors
Jae-Hwan Kim; Min-Ho Choi; Young Mee Bae; Jin-Kyoung Oh; Min Kyung Lim; Sung-Tae Hong
- Abstract
Background: Stool examination by counting eggs per gram of feces (EPGs) is the best method to estimate worm burden of Clonorchis sinensis in infected humans. The present study investigated a correlation between EPGs and worm burden in human clonorchiasis. Methods and Findings: A total of 60 residents, 50 egg-positive and 10 egg-negative, in Sancheong-gun, Korea, participated in this worm collection trial in 2006-2009. They were diagnosed by egg positivity in feces using the Kato-Katz method. After administration of praziquantel, they were purged with cathartics on the next day, and then discharged adult worms were collected from their feces. Their EPGs ranged from 0 to 65,544. Adult worms of C. sinensis were collected from 17 eggpositive cases, and the number of worms ranged from 1 to 114 in each individual. A positive correlation between EPGs and numbers of worms was demonstrated (r = 0.681, P,0.001). Worm recovery rates were 9.7% in cases of EPGs 1-1,000 and 73.7% in those of EPGs over 1,000. No worms were detected from egg-negative subjects. Maximum egg count per worm per day was roughly estimated 3,770 in a subject with EPGs 2,664 and 106 collected worms. Conclusions: The numbers of the worms are significantly correlated with the egg counts in human clonorchiasis. It is estimated that at least 110 worms are infected in a human body with EPGs around 3,000, and egg productivity of a worm per day is around 4,000.
- Subjects
CLONORCHIASIS; FECES examination; WORM eggs; FECAL occult blood tests; LAXATIVES
- Publication
PLoS Neglected Tropical Diseases, 2011, Vol 5, Issue 10, p1
- ISSN
1935-2727
- Publication type
Article
- DOI
10.1371/journal.pntd.0001339