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- Title
Non Hypoxia-Related Splenic Infarct in a Patient with Sickle Cell Trait and Infectious Mononucleosis.
- Authors
Symeonidis, Argiris; Papakonstantinou, Christos; Seimeni, Urania; Sougleri, Maria; Kouraklis-Symeonidis, Alexandra; Lambropoulou-Karatza, Chrysoula; Vagenakis, Apostolos; Zoumbos, Nicholas
- Abstract
Splenic infarction in patients with sickle cell trait is usually related to hypoxic conditions, while non-hypoxia-related infarcts are extremely rare. We report on a case of a 17-year-old male patient, living at sea level, who developed a severe left upper quadrant abdominal pain during the course of a febrile episode. On physical examination he had a mildly palpable but extremely painful spleen. A spleen scan revealed 2 areas of impaired radionucleide distribution. Hepatic enzymes were moderately increased and the IgM anti-EBV antibodies positive. Hemoglobin electrophoresis revealed the presence of 42% of hemoglobin S. A probable diagnosis of splenic infarction was established in a patient with sickle cell trait, during the course of infectious mononucleosis. The patient was treated symptomatically. The conditions of splenic congestion induced by the EBV infection and the high-grade fever may have contributed to splenic sequestration and subsequent infarcts.Copyright © 2001 S. Karger AG, Basel
- Subjects
MONONUCLEOSIS; SICKLE cell anemia; BLOOD hyperviscosity syndrome; PHYSIOLOGICAL stress; OBSTRUCTIVE lung diseases
- Publication
Acta Haematologica, 2001, Vol 105, Issue 1, p53
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000046534