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- Title
A comparison of PGC-1α mRNA and protein expression in response to 1-week endurance training on alternate days or 4 consecutive days.
- Authors
Huang, Li-Ping; Yao, Min; Wang, Ya-Li; Davie, Allan; Zhou, Shi
- Abstract
To understand the molecular mechanisms of adaptation to different training protocols, this study compared the effects of 4 sessions of 90 min treadmill exercise on alternate days or consecutive days in 1 week on messenger RNA (mRNA) and protein expression of proliferator-activated receptor-γ coactivator 1-α in rat gastrocnemius muscle. The mRNA significantly increased by 25.8-fold after alternate-day and 10.1-fold after consecutive-day training, while the protein showed no significant cumulative effect, 1.5-1.7-fold above baseline, in the 2 protocols.
- Subjects
MUSCLE proteins; CALF muscle physiology; RNA analysis; AGAR; ANIMAL experimentation; ELECTROPHORESIS; GENE expression; RESEARCH methodology; PHYSICAL fitness; POLYMERASE chain reaction; PROBABILITY theory; RATS; RESEARCH funding; STATISTICAL sampling; SPECTROPHOTOMETRY; STATISTICS; DATA analysis; TREADMILLS; DATA analysis software; DESCRIPTIVE statistics; ONE-way analysis of variance; PHYSIOLOGY
- Publication
Applied Physiology, Nutrition & Metabolism, 2015, Vol 40, Issue 11, p1210
- ISSN
1715-5312
- Publication type
Article
- DOI
10.1139/apnm-2015-0222