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- Title
The feasibility of NBI in patients with suspected upper airway lesions: A multicenter study.
- Authors
Bäck, Leif J.J.; Rekola, Jami; Raittinen, Lassi; Halme, Elina; Pietarinen, Petra; Keski‐Säntti, Harri; Aaltonen, Leena‐Maija; Mäkitie, Antti A.; Raappana, Antti; Tikanto, Jukka; Schrey, Aleksi; Grenman, Reidar; Laranne, Jussi; Koivunen, Petri; Irjala, Heikki
- Abstract
<bold>Objective: </bold>Narrow band imaging (NBI) improves diagnosis of laryngopharyngeal cancer, but most reported NBI studies are from experienced centers. Feasibility reports on use at everyday outpatient departments are needed.<bold>Study Design: </bold>Researcher-initiated, prospective, multicenter.<bold>Methods: </bold>Participating physicians were instructed in NBI technique during a 4-hour meeting. Patients underwent an examination that included endoscopy with white light (WL) high-definition (HD) TV and NBI filter in the selected time period. All suspicious lesions were biopsied. The medical records of patients with NBI negative findings were evaluated 6 months after the visit to detect all possible malignant lesions coming into view at mucosal sites. These were considered as false-negative cases, enabling long-term assess to the positive predictive value (NPV) of the protocol.<bold>Results: </bold>We enrolled 125 patients. Of those, 84 (67.2%) were males and the median age was 65 years (range, 35-91). In analysis of the accuracy of WL HD TV and NBI against biopsy, the sensitivity and specificity of WL HD TV were 62% and 81%, respectively; and the sensitivity and specificity of NBI were 100% and 84%, respectively. The diagnostic accuracy of NBI was significantly better (P < 0.05). When analyzing medical records 6 months after the initial examination, we found three patients who had been diagnosed with a malignant lesion (NPV of NBI of 96.8%).<bold>Conclusion: </bold>Narrow band imaging is readily implemented in an everyday outpatient practice, and there seems to be better detection rates of dysplastic/carcinoma lesions with HD NBI compared to HD WL.<bold>Level Of Evidence: </bold>2b. Laryngoscope, 127:1821-1825, 2017.
- Subjects
HYPOPHARYNGEAL cancer; CARCINOMA; MEDICAL records; MEDICAL care; PATIENT education
- Publication
Laryngoscope, 2017, Vol 127, Issue 8, p1821
- ISSN
0023-852X
- Publication type
journal article
- DOI
10.1002/lary.26526