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- Title
Extranodal NK/T-cell lymphoma primarily presenting as two adjacent slowly growing skin nodules with prominent epidermotropism and CD30 expression; a case report and review of literature.
- Authors
Mohammed, Arooj; Davé, Utpal; Rahnama-Moghadam, Sahand; Alomari, Ahmed K.
- Abstract
Extranodal NK/T-cell lymphoma (NKTCL) is a rarely occurring non-Hodgkin lymphoma with predilection for the nasal cavity. Cutaneous involvement, rarely occurring and often aggressive in behavior, may present as nodular mass-forming lesions with or without ulceration. Histologically, lesions are characterized by an atypical dermal lymphoid infiltrate with angioinvasion and associated necrosis. Fortuitously, Epstein-Barr virus (EBV) infection, implicated in the pathogenesis of this entity, serves as a useful diagnostic marker (i.e., Epstein Barr virus-encoded RNA in situ hybridization).
- Subjects
T-cell lymphoma; KILLER cells; SKIN tumors; DERMIS tumors; EPSTEIN-Barr virus diseases; LEG diseases; LYMPHOID tissue
- Publication
Dermatology Online Journal, 2021, Vol 27, Issue 12, p1
- ISSN
1087-2108
- Publication type
Case Study
- DOI
10.5070/D3271256701