We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Ni‐Catalyzed Regioselective Cyclotrimerization of Internal Esteryl Alkynes towards Polysubstituted Benzene Rings.
- Authors
Hou, Chao; Ma, Yan; Zhang, Yongqi; Xu, Huiling; Wu, Yuanqi; Zhao, Jinbo; Wang, Yuchao; Liu, Yu
- Abstract
Transition‐metal‐catalyzed [2+2+2] cycloaddition of alkynes is a core synthetic approach to benzene rings. Herein we describe an efficient system based on inexpensive nickel catalyst and phosphine ligand that facilitate cyclotrimerization of various internal esteryl alkynes. The regioselectivity of the protocol was precisely controlled, and a series of polysubstituted benzene rings mainly composed of 1,2,4‐isomers were provided.
- Subjects
RING formation (Chemistry); ALKYNES; BENZENE; NICKEL catalysts
- Publication
Helvetica Chimica Acta, 2022, Vol 105, Issue 5, p1
- ISSN
0018-019X
- Publication type
Article
- DOI
10.1002/hlca.202200005