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- Title
A New C13-Norisoprenoid from the Fruits of Chaenomeles sinensis.
- Authors
Li, Meng; Zhang, Zhi-guang; Shi, Jing-ya; Li, Ya-ge; Zhang, Jing-ke; Lv, Jin-jin; Zheng, Xiao-ke; Feng, Wei-sheng
- Abstract
A new C13-norisoprenoid, chaenomelesterpenoid C (1), was isolated from the fruits of Chaenomeles sinensis (Dum.Cours.) Koehne together with a known compound, linarionoside C (2). The structure of compound 1 was determined by NMR and MS analysis. Meanwhile, the protective effects of the compounds were tested against corticosterone-induced damage in PC-12 cells using real time cellular analysis (RTCA). Compounds 1 and 2 significantly improved cell viability in corticosterone-induced damaged PC-12 cells with EC50 values of 21.0 and 49.1 μM, respectively.
- Subjects
CELL analysis; FRUIT; CELL survival; CORTICOSTERONE; TIME management
- Publication
Chemistry of Natural Compounds, 2020, Vol 56, Issue 6, p1064
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-020-03227-4