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- Title
Chancen der PSMA(prostataspezifisches Membranantigen)-Hybridbildgebung beim Prostatakarzinom.
- Authors
Strauß, Anna-Sophie; Bolenz, Christian; Beer, Ambros J.; Zengerling, Friedemann; Beer, Meinrad; Miksch, Jonathan
- Abstract
Prostate-specific membrane antigen (PSMA) hybrid imaging is a promising new technique gaining importance in the field of prostate cancer (PCa) diagnosis and treatment planning. By combining PSMA radioligands and computed tomography (CT) or magnetic resonance imaging (MRI), PSMA hybrid imaging opens up new diagnostic opportunities. PSMA-PET/CT (PET: positron-emission tomography) is already well established in high-risk PCa for primary staging and tumor localization when biochemical recurrence occurs. Further potential indications for PSMA-PET/CT include tumor detection in the initial work-up before a rebiopsy with improved accuracy, the identification of target structures for precise local treatment in recurrent PCa (salvage radiotherapy or radio-guided surgery) as well as a prediction of response to PSMA radioligand therapy. This narrative review is based on a recent literature search and aims to highlight the opportunities of PSMA imaging in different disease stages of PCa.
- Subjects
PROSTATE tumors treatment; BIOPSY; MAGNETIC resonance imaging; POSITRON emission tomography computed tomography; TUMOR classification; DISEASE relapse; PROSTATE-specific membrane antigen; MEMBRANE proteins; TUMORS; SALVAGE therapy; NUCLEAR medicine; LITERATURE reviews; PROSTATE tumors; LIGANDS (Biochemistry)
- Publication
Die Urologie, 2023, Vol 62, Issue 11, p1153
- ISSN
2731-7064
- Publication type
Article
- DOI
10.1007/s00120-023-02189-z