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- Title
Polikliniklere başvuran çocuk hastaların idrar örneklerinden izole edilen bakteriler ve antibiyotiklere duyarlılıkları.
- Authors
Sanmak, Erkan; Çirkin, Gül; Orhan, Özhan
- Abstract
Objective: The aim is to identify urinary tract infection agents, assess their resistance profiles, and select suitable antibiotics for pediatric patients attending our hospital’s outpatient clinics. Material and Methods: Samples from pediatric patients who visited the outpatient clinic of Mardin Training and Research Hospital between May 1, 2021, and May 1, 2023, and showed growth in urine culture samples, were examined based on growth status, agents, and antibiotic susceptibility. Patient files were retrospectively reviewed through the hospital’s automation system. Results: Growth in urine cultures was observed in 1843 cases. The bacteria most frequently isolated were Escherichia coli (49.7%), Klebsiella spp. (13.4%), Coagulase-negative Staphylococcus (CNS) (9.7%), and Enterococcus spp. (6.9%). E. coli strains showed sensitivity to ampicillin (25.2%), ampicillin/sulbactam (50%), ceftazidime (52%), and ciprofloxacin (72.4%). The highest sensitivity in E. coli strains was observed for colistin, gentamicin, imipenem, meropenem, nitrofurantoin, and tigecycline, while the lowest was for cefazolin, cefuroxime, and ampicillin. Conclusion: There was significant resistance to first-generation cephalosporins, ampicillin, and ampicillin/sulbactam, commonly used as first-line treatments for urinary tract infections in the pediatric population. Nitrofurantoin and aminoglycosides, which exhibit low resistance, could be considered for empirical therapy. It’s crucial to use antibiotics based on indications, especially in children, and to re-evaluate treatment according to antibiotic susceptibility test results.
- Subjects
ANTIBIOTICS; URINARY tract infections; ENTEROCOCCUS; CIPROFLOXACIN; NITROFURANTOIN; MICROBIAL sensitivity tests; TIGECYCLINE; DRUG resistance in microorganisms; CEFAZOLIN; CEFUROXIME; RETROSPECTIVE studies; AMPICILLIN; COLISTIN; PEDIATRICS; ESCHERICHIA coli; URINALYSIS; GENTAMICIN; IMIPENEM; STAPHYLOCOCCUS; CEFTAZIDIME; CEPHALOSPORINS; AMINOGLYCOSIDES; KLEBSIELLA; MEROPENEM; CHILDREN
- Publication
Ümraniye Pediatri Dergisi, 2023, Vol 3, Issue 3, p145
- ISSN
2757-7074
- Publication type
Article
- DOI
10.14744/upd.2023.83803