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- Title
Recent advances in cold atmospheric plasma (CAP) for breast cancer therapy.
- Authors
Chupradit, Supat; Widjaja, Gunawan; Radhi Majeed, Basman; Kuznetsova, Maria; Ansari, Mohammad Javed; Suksatan, Wanich; Turki Jalil, Abduladheem; Ghazi Esfahani, Bahar
- Abstract
The serious problems of conventional breast cancer therapy strategies such as drug resistance, severe side effects, and lack of selectivity prompted the development of various cold atmospheric plasma (CAP) devices. Due to its advanced technology, CAP can produce a unique environment rich in reactive oxygen and nitrogen species (RONS), photons, charged ions, and an electric field, making it a promising revolutionary platform for cancer therapy. Despite substantial technological successes, CAP‐based therapeutic systems are encounter with distinct limitations, including low control of the generated RONS, poor knowledge about its anticancer mechanisms, and challenges concerning designing, manufacturing, clinical translation, and commercialization, which must be resolved. The latest developments in CAP‐based therapeutic systems for breast cancer treatment are discussed in this review. More significantly, the integration of CAP‐based medicine approaches with other breast cancer therapies, including chemo‐ and nanotherapy is thoroughly addressed.
- Subjects
LOW temperature plasmas; BREAST cancer; CANCER treatment; REACTIVE oxygen species; REACTIVE nitrogen species; NANOMEDICINE
- Publication
Cell Biology International, 2023, Vol 47, Issue 2, p327
- ISSN
1065-6995
- Publication type
Article
- DOI
10.1002/cbin.11939