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- Title
Patient-Reported Outcomes Measurement Information System (PROMIS) Assessment of Non-Motor Features in Deep Brain Stimulation Candidates: Relationship to the Beck Depression and Anxiety Inventories.
- Authors
Loring, David W; Block, Cady; Staikova, Ekaterina; Miocinovic, Svjetlana
- Abstract
Objective To compare Patient-Reported Outcomes Measurement Information System (PROMIS) measures of depression and anxiety to the Beck Depression Inventory-II (BDI-II), Beck Anxiety Inventory (BAI), and explore patterns of selected PROMIS measures in patients undergoing evaluation for Deep Brain Stimulation (DBS). Method BDI-II, BAI, and seven PROMIS measures were administered to 163 DBS candidates with diagnoses of Parkinson Disease (PD, n = 102), Essential Tremor (ET, n = 45), or Dystonia (n = 16). Results Elevated PROMIS Depression using BDI-II Crosswalk equivalents predicted elevated BDI-II with 63% sensitivity and 94% specificity. On other PROMIS measures, 69 patients (42%) reported low Physical Function (T ≤ 40) with Pain Interference being the next most frequent abnormal score (n = 51, 31%). Group differences were present for PROMIS Physical Function, Sleep Disturbance, and Pain. Conclusions These preliminary findings provide initial support for PROMIS Depression to assess mood disturbance in DBS candidates, and characterize other PROMIS measures in DBS candidates including group differences reflecting disease specific contribution to Quality of Life.
- Subjects
DEEP brain stimulation; BECK Anxiety Inventory; BECK Depression Inventory; INFORMATION storage &; retrieval systems; PHYSICAL mobility
- Publication
Archives of Clinical Neuropsychology, 2021, Vol 36, Issue 4, p632
- ISSN
0887-6177
- Publication type
Article
- DOI
10.1093/arclin/acaa091