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- Title
Addressing barriers in comprehensiveness, accessibility, reusability, interoperability and reproducibility of computational models in systems biology.
- Authors
Niarakis, Anna; Waltemath, Dagmar; Glazier, James; Schreiber, Falk; Keating, Sarah M; Nickerson, David; Chaouiya, Claudine; Siegel, Anne; Noël, Vincent; Hermjakob, Henning; Helikar, Tomáš; Soliman, Sylvain; Calzone, Laurence
- Abstract
Computational models are often employed in systems biology to study the dynamic behaviours of complex systems. With the rise in the number of computational models, finding ways to improve the reusability of these models and their ability to reproduce virtual experiments becomes critical. Correct and effective model annotation in community-supported and standardised formats is necessary for this improvement. Here, we present recent efforts toward a common framework for annotated, accessible, reproducible and interoperable computational models in biology, and discuss key challenges of the field.
- Subjects
SYSTEMS biology; COMPUTATIONAL biology
- Publication
Briefings in Bioinformatics, 2022, Vol 23, Issue 4, p1
- ISSN
1467-5463
- Publication type
Article
- DOI
10.1093/bib/bbac212