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- Title
Galektin-3: kardiologická problematika.
- Authors
A., Jabor; J., Franeková
- Abstract
Galectin-3 is mainly used in cardiology as a prognostic marker. Its pathophysiological effects correlate with the risk of cardiac fibrosis and remodelation. Elevated concentrations of galectin-3 in plasma (above the decision limit of 18 µg/L) increase the risk of cardiovascular morbidity and overall mortality, especially in patients with heart failure, myocardial infarction, heart transplantation and other cardiac diseases. The predictive value of galectin-3 increases when combined with natriuretic peptides. In cardiology, galectin-3 is recognized as a candidate molecule for prognostication.
- Subjects
NATRIURETIC peptides; HEART transplantation; GALECTINS; HEART diseases; HEART fibrosis; CHOLESTERYL ester transfer protein
- Publication
Klinická Biochemie a Metabolismus, 2022, Vol 30, Issue 4, p105
- ISSN
1210-7921
- Publication type
Article