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- Title
Sézary Syndrome in a 17-Year-Old Boy: Clinicopathologic Features and Genomic Profile.
- Authors
Alberti-Violetti, Silvia; Vezzoli, Pamela; Corti, Laura; Fanoni, Daniele; Merlo, Valentina; Venegoni, Luigia; Reseghetti, Alberto; Berti, Emilio
- Abstract
We describe the case of a 17-year-old Hispanic boy who had had erythroderma and diffuse lymphadenopathy for approximately 6 months. A diagnosis of Sézary syndrome was made on the basis of the histologic features of the skin; the presence of the same T-cell clone on the skin, blood, and bone marrow; and the high CD4+ lymphocyte count with an aberrant phenotype in peripheral blood; bone marrow involvement was also present. The patient was treated with systemic gemcitabine and achieved partial remission.
- Subjects
SEZARY syndrome; LYMPHADENITIS; T cells; BONE marrow; CD4 lymphocyte count
- Publication
Pediatric Dermatology, 2016, Vol 33, Issue 5, pe318
- ISSN
0736-8046
- Publication type
Article
- DOI
10.1111/pde.12930