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- Title
The Risk Factors Affecting Length of Stay and Mortality in Covid 19 Patients: Laboratory Parameters, Comorbidities, and Demographic Characteristics.
- Authors
Delen, Leman Acun; Erdogan, Esra; Yasar, Seyma
- Abstract
Objective: Covid 19 can cause fatal pneumonia and serious complications. In the course of the disease the levels of different biochemical parameters increased and these parameters provide important information about the prognosis of the disease. The aim of this study was to investigate the relationship between biochemical parameters and length of stay and mortality in Covid 19 patients. Methods: In this retrospective study, a total of 767 Covid 19 patients hospitalized in our hospital were included. The demographic characteristics, length of stay, comorbid diseases and biochemical parameters of the patients were scanned from the hospital's database and patient files and recorded. Patients were grouped according to the length of stay; 1st Group: 7 days and less, 2ndGroup: 8-10 days, 3rdGroup: 11-13 days, and 4thGroup: 14 days and more. Results: The mean CRP level was significantly higher in group 4 compared to group 1 (p = 0.002). The mean levels of LDH, PRO_BNP, and procalcitonin were significantly higher in group 4 compared to group 1 and group 2 (p <0.001, p = 0.026, p = 0.007, respectively). The mean level of fibrinogen was significantly higher in group 4 compared to group 2 (p = 0.011). Presence of DM and HT as comorbidities (p = 0.022, p = 0.006) and high levels of LDH and ferritin (p <0.001, p = 0.041) significantly increased the risk of death. Conclusions: The results of our study show that positive correlation between the levels of CRP, LDH, PCT, PROBNP, and fibrinogen the prolongation of hospitalization in Covid 19 patients and these parameters can be associated with the severity disease. These results show that increased levels of LDH and ferritin, age, prolongation of hospitalization, and the presence of HT and DM increase mortality rate and can be specific parameters in terms of prognosis.
- Subjects
TURKEY; MORTALITY risk factors; LENGTH of stay in hospitals; BIOCHEMISTRY; KRUSKAL-Wallis Test; STATISTICAL significance; C-reactive protein; COVID-19; PHENOMENOLOGICAL biology; AGE distribution; RETROSPECTIVE studies; CALCITONIN; RISK assessment; PEARSON correlation (Statistics); SEX distribution; SEVERITY of illness index; CHI-squared test; LACTATE dehydrogenase; FIBRINOGEN; LOGISTIC regression analysis; ODDS ratio; DATA analysis software; PEPTIDE hormones; COMORBIDITY
- Publication
Konuralp Medical Journal / Konuralp Tip Dergisi, 2021, Vol 13, p474
- ISSN
1309-3878
- Publication type
Article
- DOI
10.18521/ktd.899368