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- Title
It takes two to tango: Plant hosts influence bacterial effector function through post-translational modifications.
- Authors
Laflamme, Bradley
- Abstract
The article discusses the influence of plant hosts on the function of bacterial effectors through post-translational modifications. The researchers focused on the role of SUMOylation, a common post-translational modification in eukaryotes, in the function of effectors from the bacterial pathogen Pseudomonas syringae. They found that almost half of the tested bacterial effectors could potentially be SUMOylated once inside the plant cell. The researchers also investigated the impact of SUMOylation on the virulence activities of two specific effectors, HopB1 and HopG1, and found that SUMOylation benefited P. syringae by increasing effector virulence. Additionally, they explored the effects of heat stress on effector function and found that higher temperatures increased the requirement for SUMOylation, suggesting that the pathogen's cooption of host post-translational modifications may be of greater importance in a warming climate. The findings provide evidence for SUMOylation as a factor that regulates the interactions between plants and phytopathogenic bacteria and may have implications in understanding bacterial pathogenesis.
- Subjects
POST-translational modification; HOST plants; IMMUNE response; PLANT mitochondria; GLOBAL warming
- Publication
Plant Cell, 2024, Vol 36, Issue 6, p2051
- ISSN
1040-4651
- Publication type
Article
- DOI
10.1093/plcell/koae059