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- Title
New Tripeptide Derivatives Asperripeptides A–C from Vietnamese Mangrove-Derived Fungus Aspergillus terreus LM.5.2.
- Authors
Girich, Elena V.; Rasin, Anton B.; Popov, Roman S.; Yurchenko, Ekaterina A.; Chingizova, Ekaterina A.; Trinh, Phan Thi Hoai; Ngoc, Ngo Thi Duy; Pivkin, Mikhail V.; Zhuravleva, Olesya I.; Yurchenko, Anton N.
- Abstract
Three new tripeptide derivatives asterripeptides A–C (1–3) were isolated from Vietnamese mangrove-derived fungus Aspergillus terreus LM.5.2. Structures of isolated compounds were determined by a combination of NMR and ESIMS techniques. The absolute configurations of all stereocenters were determined using the Murfey's method. The isolated compounds 1–3 contain a rare fungi cinnamic acid residue. The cytotoxicity of isolated compounds against several cancer cell lines and inhibition ability of sortase A from Staphylococcus aureus of asterripeptides A–C were investigated.
- Subjects
ASPERGILLUS terreus; FUNGI; CELL lines; CANCER cells; STAPHYLOCOCCUS aureus
- Publication
Marine Drugs, 2022, Vol 20, Issue 1, p77
- ISSN
1660-3397
- Publication type
Article
- DOI
10.3390/md20010077