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- Title
Luminescent techniques in investigation of the biological properties of fullerene-based hybrid nanostructures.
- Authors
Kotel'nikova, R. A.; Mishchenko, D. V.; Zhokhova, D. A.; Barinov, A. V.; Goryachev, N. S.; Rybkin, A. Yu.; Bogdanov, G. N.; Varfolomeev, V. N.; Romanova, V. S.; Kotel'nikov, A. I.
- Abstract
It has been shown that amino acid derivatives of C60 fullerene (ADFs) are effective quenchers of phosphorescence of the triplet probes eosin and erythrosine. The rate constants of erythrosine phosphorescence quenching by ADFs in aqueous solutions and model membranes have been determined. Using the triplet probe technique, the ability of ADFs to be transported across the lipid bilayer into the inner space of liposomes have been revealed. By monitoring a change in the fluorescence intensity of a luminescent hybrid structure based on C60-proline and eosin, the distribution of the hybrid structure in animal organs was established. The stability of hybrid structures subjected to various chemical and biological impacts was studied by recording the fluorescence of a Gd@C82-based hybrid structure.
- Subjects
AMINO acids; FULLERENES; PHOSPHORESCENCE; FLUORESCENCE; BILAYER lipid membranes; NANOSTRUCTURES
- Publication
High Energy Chemistry, 2009, Vol 43, Issue 7, p582
- ISSN
0018-1439
- Publication type
Article
- DOI
10.1134/S0018143909070145