We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The Impact of SARS-CoV-2 Infection on the Length of Stay in the Neuro-ICU:A Prospective Multicenter Cohort Study in Eight Neuro-ICU, China Between February and April 2023.
- Authors
Tan, Liang; Wang, Feilong; Huang, Yi; Fu, Chuhua; Zhang, Haijun; Feng, Jianfei; Xu, Yincai; Ye, Xinzhen; Tang, Rongrui; Chen, Yinglian; Mou, Liansheng; Li, Ronghao; Chen, Jingyu; Xian, Jishu
- Abstract
Purpose: The SARS-CoV-2 infection cases are increasing rapidly in neuro-intensive care units (neuro-ICUs) at the beginning of 2023 in China. We aimed to characterize the prevalence, risk factors, and prognosis of critically ill patients treated in neuro-ICUs. Materials and Methods: In the prospective, multicenter, observational registry study, critically ill patients with intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), and traumatic brain injury (TBI) admitted to eight Chinese neuro-ICUs between Feb 16, 2023, to Apr 30, 2023 were enrolled for the study. Mortality and ICU stay day were used as the primary outcomes. Results: 131 patients were finally included and analyzed (mean age 60.36 years [SD 13.81], 64.12% male, 39.69% SARS-CoV-2 infected). The mortality is higher in the SARS-CoV-2 infection group without statistical signification (7.69% vs 5.06%, p> 0.05). The length of stay (LOS) in neuro-ICUs was significantly longer among the SARS-CoV-2 infection patients (7(1– 12) vs 4(1– 8), p< 0.01), with increased viral pneumonia occurrence (58.54% vs 7.32%, p< 0.01). SARS-CoV-2 infection, surgery, and low GCS scores were independent risk factors for prolonged LOS, and respiratory/renal failure were independent risk factors for death. Conclusion: Based on the present neuro-ICU cohort, SARS-CoV-2 infection was a significant risk for the prolonged LOS of neuro-critically ill patients. Trial Registration: Registered with Chictr.org.cn (ChiCTR2300068355) at 16 February 2023, Prospective registration. https://www.chictr.org.cn/showproj.html?proj=188252.
- Subjects
CHINA; SARS-CoV-2; BRAIN injuries; CEREBRAL hemorrhage; SUBARACHNOID hemorrhage; COHORT analysis; TOTAL body irradiation; GLASGOW Coma Scale
- Publication
Neuropsychiatric Disease & Treatment, 2024, Vol 20, p765
- ISSN
1176-6328
- Publication type
Article
- DOI
10.2147/NDT.S447887