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- Title
Coexistence of Xeroderma Pigmentosum with Sarcoidosis and Adenocarcinoma of the Digestive Organs.
- Authors
Okada, Mikiko; Tanaka, Misako; Horiuchi, Norihisa; Kato, Taizo; Tagami, Hachiro
- Abstract
Xeroderma pigmentosum has not been reported in association with any specific diseases except for skin malignancy. We observed a case of its coexistence with sarcoidosis and adenocarcinoma of the digestive organs, which has been reported only once in the past. A 54-year-old Japanese female with a variant type of xeroderma pigmentosum developed successively multiple lesions of basal cell carcinoma and squamous cell carcinoma on her face. Intensive metastasis studies led to the incidental detection of non-caseating epithelioid cell granulomas in one of the palpable right supraclavicular lymph nodes. Similar granulomas were also revealed in the excised tissue specimen of squamous cell carcinomas of her left cheek. She was also found to have bilateral hilar lymphadenopathy and chronic uveitis. Three years later, she died of colon adenocarcinoma and its liver metastasis.
- Subjects
XERODERMA pigmentosum; SARCOIDOSIS; ADENOCARCINOMA
- Publication
Acta Dermato-Venereologica, 2000, Vol 80, Issue 5, p376
- ISSN
0001-5555
- Publication type
Article
- DOI
10.1080/000155500459358