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- Title
Colon cancer presenting as pseudo-obstruction during pregnancy – A case report.
- Authors
Makhijani, Reeva; Bhagat, Vicky H.; Fayek, Mariam
- Abstract
The incidence of colorectal cancer in pregnancy is between 0.002 and 0.008%. Diagnosis is often delayed as symptoms of colorectal cancer can mimic as common complaints of pregnancy. We present the case of a 29-year-old with a history of chronic constipation who presented in the second trimester with abdominal pain, inability to tolerate anything orally and no bowel movement in more than three weeks. Non-contrast MRI at presentation failed to show an obstructing mass. Patient was treated conservatively for presumed pseudo-obstruction secondary to worsening constipation from chronic ondansetron use and pregnancy. After four days without clinical improvement, she had a colonoscopy that revealed a completely obstructing sigmoid mass, which biopsies confirmed was a primary colorectal adenocarcinoma. The patient underwent a total abdominal colectomy. She was referred to medical oncology and began adjuvant chemotherapy consisting of 5-fluorouracil, leucovorin and oxaloplatin four weeks post-operatively.
- Subjects
ADENOCARCINOMA; FLUOROURACIL; FOLINIC acid; OXALIPLATIN; ABDOMINAL pain; BIOPSY; COLECTOMY; COLON (Anatomy); COLON tumors; COLONOSCOPY; COMBINED modality therapy; CONSTIPATION; MAGNETIC resonance imaging; SECOND trimester of pregnancy; ONDANSETRON; RECTUM tumors; COLONIC pseudo-obstruction; SYMPTOMS; PREGNANCY; DIAGNOSIS; THERAPEUTICS
- Publication
Obstetric Medicine (1753-495X), 2017, Vol 10, Issue 4, p198
- ISSN
1753-495X
- Publication type
Article
- DOI
10.1177/1753495X17704611