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- Title
Epidemiological features of influenza in Canadian adult intensive care unit patients.
- Authors
TAYLOR, G.; ABDESSELAM, K.; PELUDE, L.; FERNANDES, R.; MITCHELL, R.; McGEER, A.; FRENETTE, C.; SUH, K. N.; WONG, A.; KATZ, K.; WILKINSON, K.; MERSEREAU, T.; GRAVEL, D.; Canadian Nosocomial Infection Surveillance Program (CNISP)
- Abstract
To identify predictive factors and mortality of patients with influenza admitted to intensive care units (ICU) we carried out a prospective cohort study of patients hospitalized with laboratory-confirmed influenza in adult ICUs in a network of Canadian hospitals between 2006 and 2012. There were 626 influenza-positive patients admitted to ICUs over the six influenza seasons, representing 17·9% of hospitalized influenza patients, 3·1/10 000 hospital admissions. Variability occurred in admission rate and proportion of hospital influenza patients who were admitted to ICUs (proportion range by year: 11·7–29·4%; 21·3% in the 2009–2010 pandemic). In logistic regression models ICU patients were younger during the pandemic and post-pandemic period, and more likely to be obese than hospital non-ICU patients. Influenza B accounted for 14·2% of all ICU cases and had a similar ICU admission rate as influenza A. Influenza-related mortality was 17·8% in ICU patients compared to 2·0% in non-ICU patients.
- Subjects
CANADA; INFLUENZA; EPIDEMIOLOGY; INTENSIVE care units; HOSPITAL administration -- Data processing; HOSPITAL admission &; discharge; PATIENTS; EVALUATION; INFLUENZA epidemiology; EPIDEMICS; HOSPITAL care; LONGITUDINAL method; LOGISTIC regression analysis
- Publication
Epidemiology & Infection, 2016, Vol 144, Issue 4, p741
- ISSN
0950-2688
- Publication type
journal article
- DOI
10.1017/S0950268815002113