We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Precipitous Deterioration of Motor Function, Cognition, and Behavior.
- Authors
Fernández-Fournier, Mireya; Perry, David C.; Tartaglia, Maria Carmela; de May, Mary; Boxer, Adam; Coppola, Giovanni; Christine, Chadwick W.; Huang, Eric J.; Seeley, William W.; Miller, Bruce L.; De Armond, Steven J.; Grinberg, Lea T.; Geschwind, Michael D.
- Abstract
A 72-year-old woman developed new-onset depression, sustained an unexplained fall, and started walking cautiously. After 1 year, her depression resolved but she developed a dry cough. One year later, she experienced amore rapid decline in her gait with parkinsonism, visual difficulties with restricted vertical gaze, slowed horizontal and vertical saccades, dysphagia, apathy, and progressive cognitive decline, which led to her death 2 years later. The differential diagnosis, neuroimaging, and pathological findings are discussed, as well as their public health implications.
- Publication
JAMA Neurology, 2017, Vol 74, Issue 5, p591
- ISSN
2168-6149
- Publication type
Article
- DOI
10.1001/jamaneurol.2016.6159