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- Title
Pityriasis lichenoides chronica Associated with Use of HMG-CoA Reductase Inhibitors.
- Authors
Massay, R. J. B.; Maynard, A. A.
- Abstract
Herein, we present three cases of Pityriasis lichenoides chronica (PLC) in patients who developed the rash after use of 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase inhibitors. The patients had complete resolution after standard treatment by dermatologists and withdrawal of the offending agents. In one case, the patient had a previous episode of a similar rash that occurred with HMG-CoA reductase inhibitors use many years previously. Pityriasis lichenoides chronica is a condition of unknown aetiology. Several agents have been associated with its presentation. We postulate HMG-CoA reductase inhibition in skin presents a final common pathway for the presentation of PLC in select patients.
- Subjects
SKIN diseases; PITYRIASIS rosea; COENZYME A; ENZYME inhibitors; DERMATOLOGISTS; REDUCTASE inhibitors
- Publication
West Indian Medical Journal, 2012, Vol 61, Issue 7, p743
- ISSN
0043-3144
- Publication type
Article