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- Title
Hepatitis C virus infection among multi-transfused patients and personnel in haemodialysis units in central Islamic Republic of Iran.
- Authors
Samimi-Rad, K.; Hosseini, M.; Mobeini, G.; Asgari, F.; Alavian, S. M.; Tahaei, M. E.; Salari, M. H.
- Abstract
A cross-sectional study was made of the prevalence of HCV and associated risk factors in 382 multi-transfused patients and haemodialysis staff in Yadz province in 2006. Of those tested for anti-HCV antibodies, 50.6% of patients with inherited bleeding disorders, 11.8% with thalassaemia and 5.0% undergoing haemodialysis were seropositive. First transfusion before 1996 (when blood donor screening started) was the common risk factor associated with HCV infection. Only 1/52 haemodialysis staff members was HCV infected (an intravenous drug user). Infection control measures were poor in all centres. In patients with inherited bleeding disorders genotype 1 (65.0%) was the predominant followed by genotype 3 (35.0%). The results provide evidence that blood donor screening and use of virus-inactivated factor concentrates have lowered the risk of HCV infection among multi-transfused patients.
- Subjects
IRAN; HEPATITIS C prevention; HEPATITIS C risk factors; HEPATITIS C transmission; PREVENTION of communicable diseases; BLOOD testing; BLOOD diseases; BLOOD transfusion; CHRONIC kidney failure; COMMUNICABLE diseases; CONFIDENCE intervals; ENZYME-linked immunosorbent assay; EPIDEMIOLOGY; GENES; HEMODIALYSIS; HEMODIALYSIS patients; HEMOPHILIA; HEPATITIS C; KIDNEY transplantation; MEDICAL personnel; MULTIVARIATE analysis; PATIENT safety; POLYMERASE chain reaction; QUESTIONNAIRES; RESEARCH funding; STATISTICS; THALASSEMIA; TIME; LOGISTIC regression analysis; DATA analysis; DISEASE prevalence; CROSS-sectional method; SEVERITY of illness index; TREATMENT duration; DATA analysis software; DESCRIPTIVE statistics; DISEASES
- Publication
Eastern Mediterranean Health Journal, 2012, Vol 18, Issue 3, p227
- ISSN
1020-3397
- Publication type
Article
- DOI
10.26719/2012.18.3.227