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- Title
Carcinoid crisis and reversible right ventricular dysfunction after embolization in untreated carcinoid syndrome
- Authors
Majeed, Farhan; Porter, Thomas R.; Tarantolo, Stefano; Duhachek-Stapelman, Amy; Xie, Feng; Elhendy, Abdou
- Abstract
Abstract: A 59-year-old white male with carcinoid tumor and hepatic metastases underwent hepatic artery embolization. The patient developed carcinoid crisis and a subsequent transthoracic echocardiogram showed classic findings of carcinoid heart disease along with a dilated hypertrophied right ventricle and severely depressed right ventricular ejection fraction. After treatment with octreotide the patient''s clinical condition improved and a repeat transthoracic echocardiogram showed a significant improvement and normalization of right ventricular systolic function. Serotonin levels showed a progressive decline that correlated well with the patient''s improved clinical condition. These findings suggest that the acute right ventricular dysfunction was secondary to acute carcinoid crisis and resolution resulted in a significant improvement of both right ventricular systolic function and clinical condition.
- Subjects
CARCINOID; LIVER metastasis; THERAPEUTIC embolization; CARCINOID heart disease; SEROTONIN; ECHOCARDIOGRAPHY
- Publication
European Journal of Echocardiography, 2007, Vol 8, Issue 5, p386
- ISSN
1525-2167
- Publication type
Article
- DOI
10.1016/j.euje.2006.04.008