We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cholesterol granuloma: a case series & review of literature.
- Authors
Shrirao, Neha; Mukherjee, Bipasha; Krishnakumar, S.; Biswas, Jyotirmay
- Abstract
Background: Cholesterol granuloma (CG) is a foreign body reaction to crystallized cholesterol. Orbitofrontal CG is a rare entity with few cases reported in literature. It is usually seen in young to middle-aged males with a history of trauma. Computed tomography features include hypodense lesion-causing bone erosion. CG has typical histopathological features with cholesterol clefts, multinucleated giant cells, histiocytes, foamy macrophages, and altered blood pigments. Management is by total excision of the lesion with curettage of the underlying bone to prevent recurrence. Material & method: We present an interventional case series of five patients of orbitofrontal CG, two of them females. Result: None of the patients gave a history of trauma. Management was by excision of the lesion and curettage confirmed with a 30° rigid endoscope. Conclusion: Cholesterol granulomas can present as superior orbital mass lesions in the absence of trauma.
- Subjects
GRANULOMA; INFLAMMATION; FOREIGN body reaction; CHOLESTEROL; COMPUTED tomography; MACROPHAGES
- Publication
Graefe's Archive of Clinical & Experimental Ophthalmology, 2016, Vol 254, Issue 1, p185
- ISSN
0721-832X
- Publication type
Article
- DOI
10.1007/s00417-015-3178-9