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- Title
Calcium oxalate: calcium phosphate transformations.
- Authors
Nancollas, George H.; Henneman, Zachary J.
- Abstract
Knowledge of the physical–chemical mechanisms responsible for the crystal growth and dissolution events involved in stone formation might enable the manipulation of thermodynamics in such a way as to increase the solubility of sparingly soluble phases (such as calcium oxalates and phosphates), thereby reducing the driving force for stone formation. This may be accomplished through modification of pH, reduction of supersaturation with respect to nucleating phases, and the presence of key inhibitors. If these modifications are made during the initial stages of crystallite nucleation, they could potentially reduce the participation of phases such as Randall’s plaques in stone formation.
- Subjects
CALCIUM oxalate; CALCIUM phosphate; CALCULI; PHOSPHATES; NUCLEATION
- Publication
Urological Research, 2010, Vol 38, Issue 4, p277
- ISSN
0300-5623
- Publication type
Article
- DOI
10.1007/s00240-010-0292-3