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- Title
Evaluating the Effect of Timing on Point-of-Care Testing of INR.
- Authors
Son, Joanne; Kim, Elise M.
- Abstract
Objectives: To evaluate if there is a difference in International Normalized Ratio (INR) readings taken within the 15 second time frame after lancing the finger vs 30-60 seconds of obtaining a blood drop utilizing a CoaguChek® XS Plus point-of-care (POC) INR machine in patients on warfarin therapy. Methods: All adult patients on anticoagulation therapy with warfarin who were managed in a pharmacist-run anticoagulation clinic were considered for inclusion in the study. The mean difference of INR readings taken less than 15 seconds vs between 30-60 seconds after the blood drop was obtained from the finger was assessed. Results: A total of 62 pairs of INR results were included in the study. There was a mean difference in INR of.076 (95% CI 0.011-.140; P =.0217) when comparing INR readings taken less than 15 seconds and between 30-60 seconds after the blood drop was obtained from the finger. Conclusions: There was a significant difference in INR readings taken less than 15 seconds vs 30-60 seconds after obtaining the blood drop when utilizing a POC INR machine. INR readings taken 30-60 seconds after obtaining a blood drop with the CoaguChek® XS Plus POC INR machine is not acceptable for use to monitor patients on warfarin.
- Subjects
WARFARIN; T-test (Statistics); DESCRIPTIVE statistics; BLOOD coagulation tests; INTERNATIONAL normalized ratio; POINT-of-care testing; DATA analysis software; CONFIDENCE intervals; TIME
- Publication
Journal of Pharmacy Practice, 2024, Vol 37, Issue 3, p703
- ISSN
0897-1900
- Publication type
Article
- DOI
10.1177/08971900231177198