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- Title
Regulatory elements: Predicting functional modules.
- Authors
Muers, Mary
- Abstract
The article discusses a study by M. Kazemian and colleagues which uses a regression-based computational model to examine cis-regulatory modules (CRMs) in a fruitfly embryo anteroposterior patterning. It mentions that the model used combines information on various elements including sequence conservation, DNA-binding specificity of transcription factors and gene expression data. Moreover, the results showed that many genes appear to contain multiple CRMs that control similar expression pattern.
- Subjects
GENETIC regulation; KAZEMIAN, M.; EMBRYOS; FRUIT flies; DNA; TRANSCRIPTION factors; GENE expression
- Publication
Nature Reviews Genetics, 2010, Vol 11, Issue 10, p669
- ISSN
1471-0056
- Publication type
journal article
- DOI
10.1038/nrg2872