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- Title
Toxic Epidermal Necrolysis associated with COVID‐19 infection: A case report.
- Authors
Jouhar, Lamia; Yahya, Marva; Elsiddiq, Sohair
- Abstract
Toxic Epidermal Necrolysis/Steven–Johnson Syndrome (TEN/SJS) is one of the most serious dermatological adverse reactions triggered mainly by drugs and less likely by infections. COVID‐19 disease is caused by Sever Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) with a wide range of clinical manifestations. Skin involvement is common in COVID‐19 patients including urticaria, purpura, and vasculitis. There were reported cases of TEN/SJS in adults with COVID‐19 infections and only two reported cases in pediatric patients. The causality relationship between COVID‐19 infection and TEN/SJS was not established in most cases due to history of drug usage that could be the trigger. In this study, we are reporting a case of previously healthy child apart from COVID‐19 infection who was admitted to the intensive care unit with TEN involving more than 30% of body surface area confirmed by skin biopsy. The child was treated with intravenous immunoglobulins, steroids, and cyclosporin with a very good outcome.
- Subjects
COVID-19; TOXIC epidermal necrolysis; COVID-19 pandemic; SYMPTOMS; MUCOCUTANEOUS lymph node syndrome; BODY surface area; URTICARIA
- Publication
Clinical Case Reports, 2022, Vol 10, Issue 3, p1
- ISSN
2050-0904
- Publication type
Case Study
- DOI
10.1002/ccr3.5565