We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Treatment for Advanced and Recurrent Endometrial Carcinoma: Combined Modalities.
- Authors
RAUH-HAIN, J. ALEJANDRO; DEL CARMEN, MARCELA G.
- Abstract
Women with recurrent or advanced endometrial cancer constitute a heterogeneous group of patients. Depending on previous treatment, women with recurrent endometrial cancer may be appropriate candidates for surgery, radiation therapy, hormonal therapy, or chemotherapy. Women with advanced stage disease at presentation may also be appropriate candidates for systemic and local therapies. We review the treatment options available to treat recurrent and locally advanced endometrial cancer. Treatment choice depends largely on the localization of disease, the patient's performance status and previous treatment history, as well the tumor's hormonal receptor status. Radiation therapy is appropriate for isolated vaginal recurrences in patients with no previous history of radiation therapy. Patients with recurrent low-grade tumors overexpressing estrogen and progesterone receptors may be treated with progestin therapy. Systemic therapy is appropriate for patients with disseminate recurrences or advanced stage disease at presentation, or for those with receptor-negative tumors. We review all these different treatment strategies available to patients with advanced or recurrent endometrial cancer.
- Subjects
ANTINEOPLASTIC agents; ENDOMETRIAL surgery; TREATMENT of endometrial cancer; CANCER relapse; COMBINATION drug therapy; COMBINED modality therapy; ENDOMETRIAL cancer; HORMONE therapy; MEDICAL education; TUMOR classification; CONTINUING education units; CLASSIFICATION; RADIOTHERAPY; DRUG therapy; CANCER treatment
- Publication
Oncologist, 2010, Vol 15, Issue 8, p852
- ISSN
1083-7159
- Publication type
Article
- DOI
10.1634/theoncologist.2010-0091