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- Title
Stress hyperglycemia, diabetes mellitus and COVID-19 infection: risk factors, clinical outcomes, and post-discharge implications.
- Authors
Athanasakis, George; Papazafiropoulou, Athanasia K.
- Abstract
There is increasing evidence that novel coronavirus disease 2019 (COVID-19) is associated with new-onset diabetes mellitus (DM). Previous outbreaks of severe acute respiratory syndrome coronaviruses showed that they are able to enter islet cells via angiotensin converting enzyme-2 receptors resulting in b-cell damage and hyperglycemia. Impaired pancreatic insulin secretion and insulin resistance have been proposed as underlying mechanisms of new-onset DM in patients with COVID-19. New-onset DM prognosis in patients with COVID-19 can be observed even in patients without risk factors for DM and it is characterized by worse prognosis and poor surveillance. Therefore, the aim of the present review is to summarize the existing literature data on the prevalence of new-onset DM in patients with COVID-19, the underlying pathogenetic mechanisms as well the management and prognosis of these patients.
- Publication
Scientific Chronicles / Epistimonika Chronika, 2021, Vol 26, Issue 4, p606
- ISSN
1791-1362
- Publication type
Article