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- Title
Antimicrobial and hemolytic activity of seaweed extracts Ulva fasciata (Delile 1813) from Mandapam, Southeast coast of India
- Authors
Priyadharshini, S; Bragadeeswaran, S; Prabhu, K; Ran, S Sophia
- Abstract
Abstract: Objective: To evaluate the In vitro antimicrobial and hemolytic activity of marine macroalgae Ulva fasciata (U. fasciata) collected from Mandapam coastal waters, and to identify certain seaweed extracts that can act as an alternative of commonly used antibiotics. Methods: Seaweeds U. fasciata was collected from Gulf of Mannar, Southeast Coastal Region, Mandapam, Tamil Nadu and was screened for antimicrobial and hemolytic activity. Methanol, butanol and aqueous extracts were tested against selected fish pathogens, Aeromonas hydrophila, Pseudomonas fluorescens, Proteus sp. Vibrio alginolyticus (V. alginolyticus) and Enterobacter sp. and fungal pathogens Rhizopus sp., Aspergillus flavus, Aspergillus sp., Aspergillus niger and Candida sp. The extract was subjected to TLC to determine the presences of peptides and amide groups. And the hemolytic activity was assayed. Results: Maximum of 16 mm inhibition zone was observed against V. alginolyticus and the minimum 12 mm against Enterobacter sp., respectively. U. fasciata showed poor activity against the fungal pathogens. The present results showed the use of seaweeds as an antimicrobial agents for pharmacology or as a health-promoting food for aquaculture. Conclusions: The screening result confirms that these seaweeds can be further studied and used as possible source of antimicrobial compounds.
- Subjects
INDIA; ANTI-infective agents; HEMOLYSIS &; hemolysins; MARINE algae; PLANT extracts; ULVACEAE; ANTIBIOTICS; BIOLOGICAL assay
- Publication
Asian Pacific Journal of Tropical Biomedicine, 2011, Vol 1, Issue S1, pS38
- ISSN
2221-1691
- Publication type
Article
- DOI
10.1016/S2221-1691(11)60118-4