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- Title
Study to investigate the potential of probiotics in children attending school.
- Authors
Merenstein, D; Gonzalez, J; Young, A G; Roberts, R F; Sanders, M E; Petterson, S
- Abstract
Background/Objectives:To determine if consumption of yogurt containing a high dose of probiotic (1 × 1010 colony-forming unit per 100 ml), Bifidobacterium animalis subsp. lactis (B. lactis), decreases absences in children 2-4 years attending daycare/school centers.Subjects/Methods:We conducted a double-blinded, randomized, placebo-controlled, allocation concealment clinical trial in the Washington, DC area. Our active intervention was a strawberry yogurt-based drink supplemented with B. lactis BB-12. The placebo was indistinguishable from the active drink, differing only in absence of the probiotic BB-12.Results:A total of 172 children between the ages of 2 and 4 from the Washington, DC area were enrolled. The primary outcome, missed days of school because of illness per 100 days, was similar in both the active (2.54 days absent/100 school days) and control groups (2.42 days absent/100 school days) (P=0.873).Conclusions:The probiotic-containing yogurt-based beverage studied did not decrease absences because of illnesses in daycare/school for healthy children ages 2-4 years.
- Subjects
PROBIOTICS; HEALTH of school children; YOGURT; BIFIDOBACTERIUM; SCHOOL attendance; CONTROL groups; PLACEBOS; RANDOMIZED controlled trials
- Publication
European Journal of Clinical Nutrition, 2011, Vol 65, Issue 4, p447
- ISSN
0954-3007
- Publication type
Article
- DOI
10.1038/ejcn.2010.290