We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Bacteriophage-Derived Vectors for Targeted Cancer Gene Therapy.
- Authors
Islam Pranjol, Md Zahidul; Hajitou, Amin
- Abstract
Cancer gene therapy expanded and reached its pinnacle in research in the last decade. Both viral and non-viral vectors have entered clinical trials, and significant successes have been achieved. However, a systemic administration of a vector, illustrating safe, efficient, and targeted gene delivery to solid tumors has proven to be a major challenge. In this review, we summarize the current progress and challenges in the targeted gene therapy of cancer. Moreover, we highlight the recent developments of bacteriophage-derived vectors and their contributions in targeting cancer with therapeutic genes following systemic administration.
- Subjects
CANCER genetics; INCURABLE diseases; CANCER education; GENE therapy; BACTERIOPHAGES
- Publication
Viruses (1999-4915), 2015, Vol 7, Issue 1, p268
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v7010268