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- Title
Development of Vitamin C-Loaded Electrospun Nanofibers of Mixture of Polysaccharides of Pullulan/Xanthan Gum for Fast Dissolving Oral Film Applications.
- Authors
Cheng, En; Geng, Zhanhui; Xiang, Lubing; Zhao, Xiaoying; Xiang, Aimin; Tian, Huafeng
- Abstract
In this study, polysaccharide-based nanofibrous fast dissolving oral films (FDOFs) were developed using pullulan (PUL) and xanthan gum (XG) via electrospinning. The edible, continuous, and bead-free nanofibers with average diameters ranging from 181.17 nm to 260.84 nm were prepared. The morphological, thermal, mechanical, and water-soluble properties of the nanofibrous FDOFs were characterized. For prospective future applications of the developed PUL/XG FDOFs, a model nutrient of vitamin C (VC) was encapsulated into the FDOFs. The success of VC encapsulation was confirmed by Fourier transform infrared spectroscopy. The encapsulation efficiency of VC was above 85% by ultraviolet-visible spectrophotometer. The amorphous structure of PUL/XG in the nanofibers film was demonstrated by X-ray diffractometer. In addition, the edible FDOFs could dissolve in water within 3 s. The nanofibers film we prepared could be used as nutrient or drug carriers and edible packaging film.
- Subjects
NANOFIBERS; XANTHAN gum; FOURIER transform infrared spectroscopy; POLYSACCHARIDES; POLYCAPROLACTONE; EDIBLE coatings; PACKAGING film; VITAMIN C
- Publication
Materials (1996-1944), 2024, Vol 17, Issue 4, p861
- ISSN
1996-1944
- Publication type
Article
- DOI
10.3390/ma17040861