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- Title
New Metabolites From the Endophytic Fungus Cercophora samala Associated With Mitragyna inermis.
- Authors
Vouffo, Erik Donfack; Douanla-Meli, Clovis; Awantu, Angelbert Fusi; Lenta, Bruno Ndjakou; Ngouela, Sylvère; Tsamo, Etienne; Laatsch, Hartmut
- Abstract
Two new natural products, mitrafungidione (1) elucidated as prototrop-isomers of (R-3-acetyl-5-ethyl-4-hydroxy-5H-furan-2-one, and maristachone F (2a), elucidated as 5-(1-hydroxyethyl)-4-(hydroxymethyl)-3-methoxy-2-methylphenol, together with 5 known compounds have been isolated from the solid cultures of an endophytic fungus associated with Mitragyna inermis (Rubiaceae) and identified as Cercophora samala. The structures of these compounds were elucidated by detailed spectroscopic analysis and by comparison of their spectroscopic data with those reported in the literature. The absolute configuration of 1 and 2a were determined by extensive DFT calculations.
- Subjects
METABOLITES; ENDOPHYTIC fungi; MITRAGYNA; RUBIACEAE; DENSITY functional theory
- Publication
Natural Product Communications, 2021, Vol 16, Issue 5, p1
- ISSN
1934-578X
- Publication type
Article
- DOI
10.1177/1934578X211013220