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- Title
N-Acetylcysteine in the prevention of ototoxicity.
- Authors
Tepel, M.
- Abstract
Prevention of ototoxicity after the administration of aminoglycoside antibiotics has been notably difficult, in particular in patients with chronic kidney disease. Feldman et al. report that oral administration of 600 mg N-acetylcysteine twice daily significantly ameliorates gentamicin-induced ototoxicity in hemodialysis patients. That approach may help to prevent aminoglycoside-induced hearing loss in these high-risk patients in daily practice.Kidney International (2007) 72, 231–232. doi:10.1038/sj.ki.5002299
- Subjects
HEARING disorders; EAR infections; DEAFNESS; AMINOGLYCOSIDES; HEMODIALYSIS patients; KIDNEY diseases
- Publication
Kidney International, 2007, Vol 72, Issue 3, p231
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/sj.ki.5002299