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- Title
FGF23 and Cause‐Specific Mortality in Community‐Living Individuals—The Health, Aging, and Body Composition Study.
- Authors
Sharma, Shilpa; Katz, Ronit; Dubin, Ruth F.; Drew, David A.; Gutierrez, Orlando M.; Shlipak, Michael G.; Sarnak, Mark J.; Ix, Joachim H.
- Abstract
Objectives: Fibroblast growth factor (FGF)‐23 is a key regulator of mineral metabolism and has been linked with left ventricular hypertrophy in animal models. Most existing epidemiologic studies evaluated a C‐terminal FGF23 assay which measures both the intact (active) hormone and inactive fragments. The relationship of intact FGF23 with cause‐specific mortality is unknown. Design: Prospective analyses of data from Health, Aging, & Body Composition (HABC) study. Setting: Community‐living adults aged 70 to 79 years with longitudinal follow up.
- Subjects
CAUSES of death; FIBROBLAST growth factors; BODY composition; AGING; CARDIOVASCULAR diseases risk factors; GROWTH factors; GLOMERULAR filtration rate
- Publication
Journal of the American Geriatrics Society, 2021, Vol 69, Issue 3, p711
- ISSN
0002-8614
- Publication type
Article
- DOI
10.1111/jgs.16910