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- Title
A quantitative analysis software tool for mass spectrometry–based proteomics.
- Authors
Sung Kyu Park; Venable, John D.; Tao Xu; Yates, III, John R.
- Abstract
We describe Census, a quantitative software tool compatible with many labeling strategies as well as with label-free analyses, single-stage mass spectrometry (MS1) and tandem mass spectrometry (MS/MS) scans, and high- and low-resolution mass spectrometry data. Census uses robust algorithms to address poor-quality measurements and improve quantitative efficiency, and it can support several input file formats. We tested Census with stable-isotope labeling analyses as well as label-free analyses.
- Subjects
MASS spectrometry; SPECTRUM analysis; PROTEOMICS; PROTEINS; ISOTOPES
- Publication
Nature Methods, 2008, Vol 5, Issue 4, p319
- ISSN
1548-7091
- Publication type
Article
- DOI
10.1038/nmeth.1195